Chinese Journal of Tissue Engineering Research ›› 2011, Vol. 15 ›› Issue (23): 4340-4343.doi: 10.3969/j.issn.1673-8225.2011.23.037

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Harvesting and differentiation potential of seed cells from adipose tissue

Zhu Xiao-fei1, Wang Yang2, Jia Li-hui3   

  1. 1Graduate Department, Liaoning Medical University, Jinzhou  121000, Liaoning Province, China; 2Department of Plastic Surgery, 3Department of Training, General Hospital of Shenyang Military Command, Shenyang  110016, Liaoning Province, China
  • Received:2011-03-01 Revised:2011-04-06 Online:2011-06-04 Published:2011-06-04
  • Contact: Jia Li-hui, Master’s supervisor, Department of Training, General Hospital of Shenyang Military Command, Shenyang 110016, Liaoning Province, China
  • About author:Zhu Xiao-fei★, Studying for master’s degree, Graduate Department, Liaoning Medical University, Jinzhou 121000, Liaoning Province, China xiaofei.987@163.com

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Abstract:

BACKGROUND: Bone marrow stromal cells (BMSCs) are considered as one kind of important seed cells in tissue engineering. At the same time BMSCs finite resource and pain while obtaining from patients has limited the application of BMSCs in tissue engineering. Adipose tissue with the plenty resource and easy to obtain has been paid more attention. Maybe seed cells derived from adipose tissue can be used generally in the future.
OBJECTIVE: To review the research on application of different kinds of seed cells derived from adipose tissue in tissue engineering.
METHODS: The first author searched articles about the isolation and differentiation potential of adipose derived stem cells, dedifferentiated adipocytes and induced pluripotent stem cells in PubMed and CQVip (2000/2010) databases by computer. 
RESULTS AND CONCLUSION: Cells derived from adipose tissue are more suitable to be seed cells for tissue engineering than BMSCs, for their availability, higher purity, and abundance in body. Nowadays, research on adipose derived stem cells is a hot spot. With the development of dedifferentiation and gene-transduction techniques, both the studies on biological characteristics and application of dedifferentiated adipocytes and induced pluripotent stem cells have made great progress. As seed cells, all three kinds of cells mentioned above can be obtained from adipose tissue, but with individual advantage and deficiency. Emphasis is placed on the contrast of acquisition and pluripotency among them, through which we can choose the ideal seed cells for tissue engineering.

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