Chinese Journal of Tissue Engineering Research ›› 2011, Vol. 15 ›› Issue (23): 4332-4335.doi: 10.3969/j.issn.1673-8225.2011.23.035

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Effect of dental stem cells involved in tissue regeneration repair

Li Ying1, Gu Zi-ya2   

  1. 1Institute of Biological Engineering, Zhejiang Academy of Medical Sciences, Hangzhou  310012, Zhejiang Province, China
    2Hangzhou Stomatological Hospital, Hangzhou  310012, Zhejiang Province, China
  • Received:2010-11-24 Revised:2011-02-24 Online:2011-06-04 Published:2011-06-04
  • About author:Li Ying★, Master, Institute of Biological Engineering, Zhejiang Academy of Medical Sciences, Hangzhou 310012, Zhejiang Province, China Liying19831121@yahoo.com.cn
  • Supported by:

    Excellent Youth Foundation of Zhejiang Academy of Medical Sciences, No. A40918E*

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Abstract:

BACKGROUND: With the development of stem cell technology, researches on dental stem cells have also come into sight. Dental stem cells are ideal resources of seed cells, which have the incomparable advantages on the application of tooth tissue engineering.
OBJECTIVE: To summarize relative research progress on dental stem cells.
METHODS: PubMed database, Highwire database and CNKI database was retrieved by the first author, with the key words of “dental stem cells, tissue engineering, application” in English and Chinese, respectively. Totally 156 literatures were initially selected, from which studies about the application of dental stem cells, including dental pulp stem cells and periodontal ligament stem cells on tissue engineering, while outdated and duplicated literatures were excluded. Finally 30 literatures were included.
RESULTS AND CONCLUSION: Various dental stem cells have the capability of self-renew and multipotential differentiation. They share many similarities with bone marrow derived mesenchymal stem cells, which are better understood currently. Therefore, dental stem cells have a promised future in tissue engineering, especially dental tissue engineering. However, there are only a few reports about application of dental stem cells on tissue regeneration, and the studies only stuck at a stage of animal models. With the development of science and technology, various dental stem cells are hopefully coming into clinical application, providing possibility to cure oral diseases of human beings.

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