Chinese Journal of Tissue Engineering Research ›› 2011, Vol. 15 ›› Issue (17): 3047-3052.doi: 10.3969/j.issn.1673-8225.2011.17.004

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Clinical outcome of Bryan artificial cervical disc replacement for the treatment of cervical spondylosis: A midterm follow-up 

Ding Chen1, Liu Hao1, Hu Tao1, Shi Rui1, Li Tao1, Hong Ying2, Song Yue-ming1, Liu Li-min1, Zeng Jian-cheng1, Kong Qing-quan1   

  1. 1Department of Orthopedics, 2Operation Room, West China Hospital of Sichuan University, Chengdu  610041, Sichuan Province, China
  • Received:2010-12-28 Revised:2011-02-12 Online:2011-04-23 Published:2011-04-23
  • Contact: Liu Hao, Professor, Doctoral supervisor, Department of Orthopedics, West China Hospital of Sichuan University, Chengdu 610041, Sichuan Province, China liuhao6304@163.com
  • About author:Ding Chen☆, Studying for doctorate, Physician, Department of Orthopedics, West China Hospital of Sichuan University, Chengdu 61004, Sichuan Province, China dclxm_84213@163.com

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Abstract:

BACKGROUND: Although the short-term clinical efficacy of Bryan artificial cervical disc replacement is generally acknowledged by most spinal surgeons, the midterm and long term clinical results and complications are still unclear.
OBJECTIVE: To summarize midterm term clinical results of Bryan artificial cervical disc replacement for the treatment of cervical spondylosis.
METHOD: From November 2004 to December 2007, 34 patients had Bryan cervical disc replacement in Department of Orthopedics, West China Hospital were selected, including 30 cases with single replacement and 4 cases with bi-level replacement. Clinical result was evaluated by SF-36 score, JOA score, and neck/arm pain VAS scores. And the data was collected before surgery and at 7 days, 3, 6, 12, 24, 36 and 48 months after surgery. Neutral lateral and dynamic cervical radiographs were made to measure the flexion-extension range of motion (ROM) of operative segment, adjacent segments and C2-7 segment, the intervertebral height of operative and adjacent segments, and the translation of operative level. The intraoperative and postoperative complications were recorded and analyzed.
RESULTS AND CONCLUSION: The neurological symptoms of each patient were alleviated notably. The postoperative SF-36 physical component score and SF-36 mental component score, JOA score, NDI score and neck/arm pain VAS scores were significantly improved compared with those of the preoperative (P  < 0.05), but no statistical significance were noted between each time point after 3-month follow-up (P  > 0.05). Each implanted prosthesis preserved the ROM>2° at each follow-up time point, and no heterotopic ossification or spontaneous fusion was found at the operative segment. At 48-month follow-up, flexion-extension ROM of operative segment and C2-7 segment slightly increased but showed no statistical significance compared with the preoperative counterparts (P > 0.05); ROM of upper and lower adjacent segments also showed no statistical significance compared with the preoperative data (P > 0.05). Intervertebral height of operative segment was (6.04±1.02) mm before the operation and significantly increased to (8.44±0.43) mm at 48-month follow-up (P  < 0.05). Intervertebral height of adjacent segments, and the translation of operative level were not significantly changed (P  > 0.05). The clinical result of Bryan artificial cervical disc replacement is good and kinematic characteristics of operative segment, adjacent segments and C2-7 segment can be maintained in midterm follow-up. The operation is safe and there are few early midterm complications.

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