Chinese Journal of Tissue Engineering Research ›› 2011, Vol. 15 ›› Issue (16): 3017-3019.doi: 10.3969/j.issn.1673-8225.2011.16.040

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Factorial analysis of different meshes for repair of inguinal hernia

Zhang Wei-yu   

  1. Second Department of General Surgery, Zhongda Hospital, Southest University, Nanjing  210009, Jiangsu Province, China
  • Received:2010-10-19 Revised:2011-03-20 Online:2011-04-16 Published:2011-04-16
  • About author:Zhang Wei-yu, Physician, Second Department of General Surgery, Zhongda Hospital, Southest University, Nanjing 210009, Jiangsu Province, China zhangwy10@139.com

Abstract:

BACKGROUND: At present, there are many kinds of surgical meshes, including nonabsorbable materials, absorbable materials, and composite materials. In order to choose the optimal mesh for patients with inguinal hernia, a physician need to be familiar with characteristics of various biomaterials.
OBJECTIVE: To evaluate the effect of different mesh materials on inguinal hernia in order to master properties of various mesh materials for individual treatment.
METHODS: There were two investigated factors: hernia type and mesh materials. The mesh materials included polypropylene (PP), EPTFE, and acellular dermal matrix tablets. The hernia types were inguinal hernia and direct inguinal hernia. The experiment design was according to 2 × 3 factorial experimental design, and the indexes were average operation time, recurrence rate, and surgical complications. Statistical analysis was done by SPSS 10.0 software.
RESULTS AND CONCLUSION: There were significant differences among PP, EPTFE, and acellular dermal matrix tablets based on the indicators of average operation time and complication incidence (P< 0.05); however, no difference occurred between inguinal hernia and direct inguinal hernia (P > 0.05). These findings indicated that material properties and patients’ manifestations are the key factors to the selection of mesh materials.

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