Abstract:

OBJECTIVE: To analyze the effects of nano-silver gel on vaginitis and cervical erosion at different levels and different types, and to compare the efficacy of LEEP combined with nano-silver and simple LEEP in treatment of gynecological diseases.
METHODS: Relevant articles published in 2006-01/2010-12 were searched using “nano-silver; nano-silver gel; vaginitis; cervicitis” as keywords. Repetitive articles and Meta-analysis were excluded. Twenty-five articles were included.
RESULTS: Nano-silver gel is prepared by advanced nanotechnology, about 25 nm in diameter, and characterized as quantum effect, small size effect and large surface area, easy to be absorbed. Nano-silver gel can form a protective membrane in the vaginal and cervical parts, which can kill pathogenic microorganisms, reduce vaginal discharge and shorten the time of vaginal discharge.
CONCLUSION: The nano-silver preparation is safe with broad-spectrum and highly effective antibacterial and sterilization, which is easy for patients. However, the biological safety of nano-silver has yet needed further studies.