Chinese Journal of Tissue Engineering Research ›› 2010, Vol. 14 ›› Issue (34): 6401-6404.doi: 10.3969/j.issn.1673-8225.2010.34.032

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Material characteristics of cardiovascular stent-graft and its treatment for aortic dissection

Li Le-wen, Zhang Yan, Wang Jia-kun   

  1. Hainan Cadre Sanatorium, Haikou   571100, Hainan Province, China
  • Online:2010-08-20 Published:2010-08-20
  • About author:Li Le-wen, Associate chief physician, Hainan Cadre Sanatorium, Haikou 571100, Hainan Province, China lilewen1965@hotmail.com

Abstract:

OBJECTIVE: To investigate the material characteristics of the cardiovascular stent-graft and the clinical application of stent placement for the treatment of aortic dissection.
METHODS: Wanfang Database and China Academic Journal Full-text Database were retrieved on computer by the first author using the key words of “aortic dissection; stent-graft; biological materials; clinical research; complications” in Chinese between 1998 and 2010 for articles related to stent-graft treatment for aortic dissection. The repeated study or old literatures were excluded.
RESULTS: According to inclusion and exclusion criteria, 18 literatures were included. Stent-graft is a product of metal or alloy stent endovascular stent with artificial (natural) membrane structure, which is often coated with polyester and biofilm. Polyester is easily obtained, low-cost, but lacks flexibility and can not expand, may induce thrombosis; biofilm has good biocompatibility, and can promote endothelial growth, is the most potential membrane. As for the clinical application curative effect, stent-graft treatment of aortic dissection achieves good results.
CONCLUSION: The endovascular stent-graft can effectively treat Stanford B type/Debakey III type aortic dissection, it is a safe and effective minimally invasive therapy, but long-term effects still need long-term and close follow-up study to be confirmed.

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