Chinese Journal of Tissue Engineering Research ›› 2010, Vol. 14 ›› Issue (33): 6143-6146.doi: 10.3969/j.issn.1673-8225.2010.33.015

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Effect of interval hypoxic training on cardiac function of rats

Liu Wei1, Zhou Li2   

  1. 1 Department of Physical Education, Xi’an University of Science and Technology, Xi’an  710054, Shaanxi Province, China; 2 Department of Sports and Body Sciences, Xi’an Institute of Physical Education, Xi’an  710048, Shaanxi Province, China
  • Online:2010-08-13 Published:2010-08-13
  • About author: Liu Wei★, Master, Teaching assistant, Department of Physical Education, Xi’an University of Science and Technology, Xi’an 710054, Shaanxi Province, China 583740365@qq.com

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Abstract:

BACKGROUND: Previous studies demonstrated that interval hypoxic training (IHT) can increase aerobic performance via altering blood index, but most of these are focus on researching blood index, the effects of IHT on cardiac function remain poorly understood.
OBJECTIVE: To investigate the effect of IHT on the cardiac function by testing of hemodynamic parameters.
METHODS: Female Sprague Dawley rats were randomly divided into the control, IHT, sports, and IHT + sports groups. No treatment was performed on rats in the control group. IHT was performed in the IHT group. Rats were forced swimming without load in the sports group. In the IHT + sports group, rats were forced IHT and sports. The cardiac functions of rats were tested at 4 weeks after training.
RESULTS AND CONCLUSION: The hemodynamic parameters of rats were altered with different degrees in all groups exception of the control group. The left ventricle systolic pressure, left ventricle end-diastolic pressure, left ventricle the maximal rates of pressure fall, left ventricle the maximal rates of rise and cardiac index of the IHT + sports group were higher than those of the other groups (P < 0.05). These findings revealed that IHT plus sport can increase cardiac systolic and diastolic functions.

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