Abstract:

OBJECTIVE: To explore the contraceptive effect of new reversible contraceptive device on oviduct and side effects caused by subcutaneous implants of controlled-release contraceptive drugs.
METHODS: A computer search was performed by the first author among Wanfang database (http://med.wanfangdata.com/) for articles about oviductal contraception and subcutaneous implantation of controlled-release contraceptive drugs. The retrieval time was 1998-01/2010-04. Key words are contraceptive device on oviduct; subcutaneous implants; slow-release contraceptive drugs. Totally 23 literatures were selected for further analysis.
RESULTS: The contraceptive device on oviduct made of nickel titanium alloy, polyethylene and other polymer materials, are safe and well histocompatible, present with a smooth placing, well positioned and easy dislodge. Subcutaneous implants for contraception is an efficient, long-lasting, safe, simple, reversible method, which is deeply welcomed by the women at reproductive age, with less breakage upon dislodging. However, further studies are needed to determine side effects.
CONCLUSION: With the continuous development of new materials and techniques, it is an increasing requirement to produce excellent contraceptive system, with less side effects, so as to achieve better outcome in clinical application.