Abstract:

OBJECTIVE: To explore the cause and prevention of deep venous thrombosis.
METHODS: A computer-based online search of VIP database was performed for articles related to the formation and prevention of deep venous thrombosis following artificial joint replacement, published between January 1998 and October 2009, with the key words “deep venous thrombosis, cause, diagnosis, prevention”. The data were collected, and references of each article were reviewed. A total of 26 articles were included.
RESULTS: Deep venous thrombosis following joint replacement is related to age, gender, cancer history, previous thrombosis, obesity index, anesthesia approach, bone cement, operation and trauma. Bed rest, affect limb raising, anticoagulation, thrombolysis and thrombus removal by operation can be used to prevent thrombus. The combination of above two or three methods has been recommended.
CONCLUSION: Monitor of early deep venous thrombosis and systematic anticoagulation are important for venous thrombosis prevention. However, there remains no medicine (or combination application) that can treat deep venous thrombosis following joint replacement. The best medicine and medication pattern require further exploration.