Chinese Journal of Tissue Engineering Research ›› 2010, Vol. 14 ›› Issue (22): 4027-4031.doi: 10.3969/j.issn.1673-8225.2010.22.009

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Evoked potential analysis and dipole localization by magnetic stimulation on acupoint of Shenmen (HT 7) acupoint

Geng Yue-hua, Xu Gui-zhi, Yu Hong-li, Chen Ya-jing, Li Wen-wen   

  1. Key Laboratory of Electro-Magnetic Field and Electrical Apparatus Reliability of Hebei Province, Hebei University of Technology, Tianjin   300130, China
  • Online:2010-05-28 Published:2010-05-28
  • Contact: Xu Gui-zhi, Doctor, Professor, Key Laboratory of Electro-Magnetic Field and Electrical Apparatus Reliability of Hebei Province, Hebei University of Technology, Tianjin 300130, China gzxu@hebut.edu.cn
  • About author:Geng Yue-hua☆, Studying for doctorate, Lecturer, Key Laboratory of Electro-Magnetic Field and Electrical Apparatus Reliability of Hebei Province, Hebei University of Technology, Tianjin 300130, China gyh@hebut.edu.cn
  • Supported by:

    the Natural Science Foundation of Hebei Province, No. E2008000053*, E2009000049*; the National Natural Science Foundation of China, No. 50877023*; Science & Technology Pillar Program of Hebei Province, No. 09276103D-4*

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Abstract:

BACKGROUND: Magnetic stimulation is a new kind of non-invasive and painless stimulation technique, which can substitute acupuncture or electric acupuncture. Electroencephalogram (EEG) can show the active state of brain nerves, thus, magnetic stimulating acupoint related to brain nerves, measuring and analyzing the EEG signals can study the effect of magnetic stimulation on acupoint.
OBJECTIVE: To stimulate acupoint of Shenmen (HT 7) using magnetic stimulation with different frequencies, in addition, to study the evoked potentials (EPs) and dipole localization of EEG at 4 states.
METHODS: A total of 6 male and 4 female volunteers were selected, aged 20-30 years. They had no experimental experience or formal psychiatric history. They kept eyes closing during the experiment. Magnetic stimulate acupoint of Shenmen (HT 7) at right hand of volunteers in frequencies of 3 Hz, 1 Hz and 0.5 Hz. The experiment of every frequency was divided into 4 tests: quiet, magnetic stimulation, mock stimulation and mock point. The amplitude and latency of EPs at 4 states and the coronal, sagittal and axial plane of dipole localization of EPs were observed.
RESULTS AND CONCLUSION: The 4-states experiments of 0.5 Hz and 1 Hz had no obvious EPs. Quiet state and mock stimulation state of 3 Hz had no obvious EPs. Magnetic stimulation state induced EP of P300, somatosensory evoked potentials and other potentials were restrained. Mock point induced P300 and also induced obvious SEPs and other potentials. Dipole localized to magnetic stimulation state and mock point state. It can be defined that there are two dipoles by Principal Components Analysis PCA. The dipoles of magnetic stimulation state located in frontotemporal area, the dipoles of mock point state were dispersed. The EEG signals were obviously restrained when magnetic stimulate on acupoint of Shenmen (HT 7). It also has the effect of adjusting neural function the same as acupuncture.

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