Chinese Journal of Tissue Engineering Research ›› 2011, Vol. 15 ›› Issue (29): 5437-5440.doi: 10.3969/j.issn.1673-8225.2011.29.029

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Effects of levonorgestrel-releasing intrauterine system in treating gynecological diseases

Li Guang-hua, He Jin-liang   

  1. Department of Gynaecology and Obstetrics, Nanchang Second Hospital, Nanchang  330002, Jiangxi Province, China
  • Received:2011-02-01 Revised:2011-04-18 Online:2011-07-16 Published:2011-07-16
  • About author:Li Guang-hua, Attending physician, Department of Gynaecology and Obstetrics, Nanchang Second Hospital, Nanchang 330002, Jiangxi Province, China hxq33@126.com

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Abstract:

BACKGROUND: Levonorgestrel-releasing intrauterine system is reliable in contraception by inhibiting endometrium.
OBJECTIVE: To elucidate effects of levonorgestrel-releasing intrauterine system in treating gynecological diseases.
METHODS: A computer-based online search of CBM, PubMed database (http://www.ncbi.nlm.nih.gov/PubMed), Wanfang database (http://www.wanfangdata.com.cn), and google search was performed for articles related to levonorgestrel-releasing intrauterine system in treating gynecological diseases, published between 1990 and 2010. Repetitive studies were excluded.
RESULTS AND CONCLUSION: A total of 17 articles were included. As intrauterine progestogen-releasing system, levonorgestrel-releasing intrauterine system can be used as a safe and effective contraception method. In addition, it can treat menorrhagia, endometriosis, adenomyosis, protect endometrium, and ameliorate hysteromyoma-induced menorrhagia. Results revealed that levonorgestrel-releasing intrauterine system can effectively treat gynecological diseases. However, large-sample, long-term clinical studies are required.

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