Abstract:

BACKGROUND: For the repair of severe or complicated acute bone injury, the ideal choice of bone matrix materials provides an ideal living environment for the cells.
OBJECTIVE: To review the application and surface modification of bone tissue engineering matrix materials.
METHODS: A computer search of CNKI and PubMed (1999-01/2011-03) was performed to find articles addressing cartilage injury and medical suture materials using the keywords of “bone, materials, modified” in Chinese and English. Articles published in the recent or in authorized journals were preferred. Finally, 28 of 237 articles were included.
RESULTS AND CONCLUSION: Ideal bone matrix materials must have good biocompatibility, appropriate hardness, and can provide an ideal environment for cell adsorption, regeneration and reproduction. The advantages and disadvantages in the use of various bone matrix materials still exist. Therefore, in order to achieve the desired result of the matrix material, to select the desired matrix material is particularly critical, and necessary surface modification is required to meet the ideal matrix material needs.