Chinese Journal of Tissue Engineering Research ›› 2010, Vol. 14 ›› Issue (33): 6190-6193.doi: 10.3969/j.issn.1673-8225.2010.33.027

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Tissue-engineered bone in oral implantology

Li Yang1, Li Zhao2   

  1. 1 Department of Quality Management, General Hospital of Beijing Military Command, Beijing  100700, China; 2 Department of Endodontics, Nanyang Stomatology Hospital, Nanyang  355762, Henan Province, China
  • Online:2010-08-13 Published:2010-08-13
  • Contact: Li Zhao, Master, Attending physician, Department of Endodontics, Nanyang Stomatology Hospital, Nanyang 355762, Henan Province, China zhaoli5654114@yahoo.com.cn
  • About author:Li Yang★, Master, Physician, Department of Quality Management, General Hospital of Beijing Military Command, Beijing 100700, China

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Abstract:

BACKGROUND: In the oral implantology, the planting site is usually lack of bone. Tissue-engineered bone has made a progress in the lack of bone of planting site. 
OBJECTIVE: To overview the composition and application of tissue-engineered bone in the oral implantology from aspects of seed cells, scaffold materials, and growth factors.
METHODS: VIP and PubMed databases were searched by computer using key words of “tissue-engineered bone, oral implantology” for papers published from 2000 to 2009. The repetitive documents were excluded.
RESULTS AND CONCLUSION: Totally 258 literatures were searched by computer, and 25 documents were included in the final analysis. Bone, cartilage, periosteum, extraosseous tissues and fetal bone are the main sources of seed cells. Application of growth factors can induce, accelerate, and enhance the formation of alveolar bone. The synthetic materials are widely used in preparing scaffolds, thus, the repair effects are diversified using different materials. Tissue-engineered bone possesses good prospect due to small donor tissues and few rejections, however, it encounters the problems of great technical difficulty and slow growth speed.

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