Chinese Journal of Tissue Engineering Research ›› 2011, Vol. 15 ›› Issue (26): 4885-4890.doi: 10.3969/j.issn.1673-8225.2011.26.034

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Effects of CO2 laser moxibustion on quality of life in patients with knee osteoarthritis: A double-blind randomized controlled trial

Wu Fan1, Zhang Hai-meng1, Wang Li-zhen1, Zhao Ling1, Deng Hai-ping1, 2, Cheng Ke1, 2, Shen Xue-yong1, 2   

  1. 1Shanghai University of Traditional Chinese Medicine, Shanghai  201203, China
    2Shanghai Research Center of Acupuncture and Meridian, Shanghai  201203, China
  • Received:2011-04-18 Revised:2011-05-27 Online:2011-06-25 Published:2011-06-25
  • Contact: Shen Xue-yong, Professor, Doctoral supervisor, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China; Shanghai Research Center of Acupuncture and Meridian, Shanghai 201203, China snowysh@hotmail.com
  • About author:Wu Fan☆, Studying for doctorate, Assistant teacher, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China lunchwf@hotmail.com
  • Supported by:

    the National 973 Program of China, No. 2009CB522901*; State Administration of TCM and Shanghai Leading Academic Discipline Project, No. S30304*; Youth Science and Technology Venus Project of Shanghai, No. 10QA1406400*; the National Natural Science Foundation of China, No. 30801489*; Shanghai Special Fund for College selection and Training of Outstanding Young Teachers, No. szy08022*; the Scientific and Technological Project of Shanghai Science and Technology Development Fund, No. 08DZ1972801*, 08DZ1973000*

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Abstract:

BACKGROUND: Currently, there are only a few clinical reports on the efficacy of laser moxibustion for knee osteoarthritis, and most of them focus on pain and joint function improvement after treatment. The life quality of patients is rarely observed or reported only as a minor measurement.
OBJECTIVE: To observe effects of CO2 laser moxibustion on quality of life in patients with knee osteoarthritis.
METHODS: Thirty-one cases were included in accordance with the inclusion criteria and divided into a treatment group (15 cases, with CO2 laser moxibustion treatment on ST-35) and a control group (16 cases, without laser treatment) with a double-blind, randomized and controlled method. Patients of both groups received 20 minutes’ treatment, thrice a week and 4 weeks in total.
RESULTS AND CONCLUSION: Scores of physical functioning (PF) in the treatment group was significantly improved after 4 weeks’ treatment as well as in the follow-up (P=0.031, P=0.006). Scores of bodily pain (BP) and general health (GH) in the treatment group was significantly superior in the follow-up compared with those before treatment (P=0.007, P=0.011). After 2 weeks’ treatment, scores of PF and role limitations-physical (RF) in the observation group was significantly superior to those in the control group (P=0.033). Significant difference was also presented in scores of PF in the follow-up between two groups (P=0.021). Scores of BP in the treatment group showed higher tendency of improvement than that of the control group (P=0.037). Compared with the control group, CO2 laser moxibustion treatment could better improve quality of life in patients with knee osteoarthritis in respect of bodily function and pain.

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