Chinese Journal of Tissue Engineering Research ›› 2011, Vol. 15 ›› Issue (26): 4857-4859.doi: 10.3969/j.issn.1673-8225.2011.26.027

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Meaning of pH value of the knee joint fluid in the crystal formation of gout

Xiao Ying, Zhang Si-rong, Tang Zhi-hong, Zou Guo-yao, Li Zheng, Liu Rui-duan, Liu Lei   

  1. Department of Orthopaedics and Spine Surgery, Affiliated Hospital of Guilin Medical University, Guilin  541001, Guangxi Zhuang Autonomous Region, China
  • Received:2011-02-11 Revised:2011-05-14 Online:2011-06-25 Published:2011-06-25
  • Contact: Tang Zhi-hong, Master’s supervisor, Department of Orthopaedics and Spine Surgery, Affiliated Hospital of Guilin Medical University, Guilin 541001, Guangxi Zhuang Autonomous Region, China
  • About author:Xiao Ying★, Master, Attending physician, Department of Orthopaedics and Spine Surgery, Affiliated Hospital of Guilin Medical University, Guilin 541001, Guangxi Zhuang Autonomous Region, China 39668731@qq.com
  • Supported by:

    the Scientific Research Project of Guangxi Education Bureau, No. 200911LX302*; the Self-raised Project of Guangxi Health Bureau, No. 2009037*; Science Research and Technology Development of Guilin City, No. 20090204*

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Abstract:

BACKGROUND: There should be other factors influencing crystallization of gout besides increase of uric acid concentration
OBJECTIVE: To explore the meaning of pH value of the knee joint fluid in the crystal formation of gout.
METHODS: We tested and compared the pH values of experiment group (25 hyperuricemia patients, with gout crystals in joint fluid) and control group (15 hyperuricemia patients, without gout crystals in joint fluid).
RESULTS AND CONCLUSION: The pH value of experiment group (7.8±0.2) was less than that of control group (8.6±0.3). The pH value of the knee joint fluid of patients with gout crystals in their knee joint was significantly lower than that of patients without gout crystals in their knee joint (P < 0.001). The lower pH value of the knee joint fluid, the more possibility of gout crystals. Low pH value of the knee joint fluid is one of the risk factors for crystallization of gout.

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