Chinese Journal of Tissue Engineering Research ›› 2011, Vol. 15 ›› Issue (26): 4757-4762.doi: 10.3969/j.issn.1673-8225.2011.26.003

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Biomechanical effect of simulative percutaneous vertebroplasty on adjacent vertebras: A finite element analysis about thoracolumbar osteoporotic vertebra compression fracture

Fei Qi1, Wang Bing-qiang1, Yang Yong1, Tang Hai1, Li Jin-jun1, Wang Yi-peng2, Li Dong1   

  1. 1Department of Orthopaedics, Beijing Friendship Hospital, Capital Medical University, Beijing  100050, China
    2Department of Orthopaedics, Peking Union Medical College Hospital, Beijing  100730, China
  • Received:2011-02-10 Revised:2011-05-07 Online:2011-06-25 Published:2011-06-25
  • Contact: Li Dong, Associate chief physician, Department of Orthopaedics, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China osteodong@bbn.cn
  • About author:Fei Qi☆, Doctor, Associate chief physician, Department of Orthopaedics, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China feiqi@medmail.com.cn Wang Bing-qiang, Department of Orthopaedics, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China Fei Qi and Wang Bing-qiang contributed equally to this paper.
  • Supported by:

    Youth Research Project Fund of Beijing Health Bureau in 2010, No. QN2010-007*

Abstract:

BACKGROUND: Is adjacent vertebral fracture following percutaneous vertebroplasty (PVP) a development process of osteoporosis or caused by enhanced bone cement and PVP?
OBJECTIVE: To explore the biomechanical effects on adjacent vertebras of thoracolumbar osteoporotic vertebra compression fracture (OVCF) after simulative PVP by using finite element analysis.
METHODS: T10-L2 segment data were obtained from CT scans of an old female with single T12 OVCF. A three-dimensional finite element model of thoracolumbar spine (T10-L2) and simulative PVP models (via single and double transpedicular approach) were built in the Mimics and the ABAQUS software. The stress on the vertebra, disc and endplate under axial pressure (0.3, 1.0, 4.0 MPa) were analyzed.
RESULTS AND CONCLUSION: The three-dimensional finite element models of thoracolumbar OVCF and simulative PVP models were successfully built. The stresses were increased as axial pressure increased. In the model of simulative PVP, the stress augmentation scope on adjacent vertebras and discs did not increase. The maximum Von Mises stress on adjacent vertebras had no significant changes. Postoperative adjacent vertebral fractures after PVP may be poorly related to the changes of biomechanical effects on adjacent vertebras of thoracolumbar OVCF.

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