Chinese Journal of Tissue Engineering Research ›› 2011, Vol. 15 ›› Issue (22): 4098-4102.doi: 10.3969/j.issn.1673-8225.2011.22.026

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A programmable and implantable neuromuscular electrical stimulator for denervated or neuromuscular electrical stimulation in animal models

Song Guang, Wang Lei, Ren Chao-shi, Sha Hong   

  1. Bioinformation Measurement and Processing Laboratory, Institute of Biomedical Engineering, Chinese Academy of Medical Science and Peking Union Medical College, Tianjin  300192, China
  • Received:2011-03-06 Revised:2011-04-03 Online:2011-05-28 Published:2011-05-28
  • Contact: Sha Hong, Master, Investigator, Master’s supervisor, Bioinformation Measurement and Processing Laboratory, Institute of Biomedical Engineering, Chinese Academy of Medical Science and Peking Union Medical College, Tianjin 300192, China sha_hong_2000@hotmail.com
  • About author:Song Guang★, Studying for master’s degree, Bioinformation Measurement and Processing Laboratory, Institute of Biomedical Engineering, Chinese Academy of Medical Science and Peking Union Medical College, Tianjin 300192, China song_job@163.com

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Abstract:

BACKGROUND: Implantable neuromuscular electrical stimulator is a useful tool for the study how functional electrical stimulation works on denervated muscle. However, its volume is a little big and the function is single.
OBJECTIVE: To design an implantable micro-stimulator featuring adjustable parameters which can reach the requirement of animal pattern experiment through test and analysis.
METHODS: Based on infrared communication technology, taking MSP430 as controller and setting stimulation parameters by controller in vitro, it generates charge balanced bipolar pulses, and stimulates nerve or muscle via electrodes.
RESULTS AND CONCLUSION: The stimulator is programmable in vivo and all parameters, such as voltage amplitude, frequency, pulse width and rest time of the stimulation, can be set and changed flexibly. It enriches selectivity of stimulating protocol by setting parameters, so that the unpredictable stimulation to the tissue around the target neuromuscular is minimized, the design of current consumption is optimized and the safety of experimental animals is ensured.

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