Chinese Journal of Tissue Engineering Research ›› 2011, Vol. 15 ›› Issue (19): 3581-3585.doi: 10.3969/j.issn.1673-8225.2011.19.039

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Effect of stem cells and strategy of traditional Chinese medicine in cardiac regenerative medicine 

Yao Kui-wu1, Wang Jie1, Zhang Liang-deng1, 2   

  1. 1Department of Cardiology, Guang’anmen Hospital, China Academy of Chinese Medical Sciences, Beijing  100053, China
    2School of Acupuncture and Moxibustion, Beijing University of Chinese Medicine, Beijing  100029, China
  • Received:2010-11-08 Revised:2010-12-19 Online:2011-05-07 Published:2011-05-07
  • Contact: Zhang Liang-deng, Studying for master’s degree, Department of Cardiology, Guang’anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, China; School of Acupuncture and Moxibustion, Beijing University of Chinese Medicine, Beijing 100029, China zldeng3@sohu.com
  • About author:Yao Kui-wu☆, Doctor, Associate chief physician, Department of Cardiology, Guang’anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, China kuiwuyao@yahoo.com.cn
  • Supported by:

    the Capital Medical Development Scientific Research Fund, Beijing Medical Science Technology Association Program, No. SF-2007-Ⅰ-04*

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Abstract:

BACKGROUND: Traditional Chinese medicine (TCM) has its unique understanding on cardiac regeneration, but there is preliminary exploration stage of stem cells and cardiac regenerative medicine intervention in TCM.
OBJECTIVE: To analyze and summarize correlative research development of stem cells and cardiac regeneration, and preliminarily discuss how to intervene cardiac regeneration in TCM.
METHODS: PubMed database was searched with the key words “stem cell, cardiac regenerative medicine” and China National Knowledge Infrastructure with the key words “stem cell, TCM” for literatures published between 2000 and 2010, no limitation in language. We analyzed and summarized the literatures evidence that met criterions. Finally, 43 articles were included.
RESULTS AND CONCLUSION: The analysis demonstrated that the study of use of stem cells in cardiac regenerative medicine has been expanded widely, including embryonic stem cells, bone marrow stem cells, adult cardiac stem cells, et al, which indicate the ability to regenerate myocardium and application perspectives. The understanding on cardiac regeneration in TCM is contained in yin and yang concept, the law of mother and son in five elements and vital essence theory. TCM needs to collate the understanding of cardiac regenerative medicine in TCM theory systematically, TCM compounds, value active components of TCM targeting to stem cells and to enhance researches on mechanisms of effective TCM.

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