Abstract:

BACKGROUND: Injection therapy for stress urinary incontinence is a minimally invasive means of treatment, but because of previous vaccination materials restriction, there are many complications, with poor long-term effects. It is significant to search new injection materials.
OBJECTIVE: To retrospectively analyze the research of stress urinary incontinence using muscle-derived stem cells.
METHODS: The first author retrieved PubMed database, Springer database and China National Knowledge Infrastructure for articles concerning muscle-derived stem cells for treatment of stress urinary incontinence published from 2003 to 2010. The key words were “stress urinary incontinence, muscle-derived stem cell”. A total of 40 articles were retrieved primarily by computer, and 24 articles were finally included for review according to inclusion criteria.
RESULTS AND CONCLUSION: Treatment method of stress urinary incontinence mainly included non-surgery therapy and surgery therapy. The surgery treatment exists many complications, even risk for overcorrect. However, the injection therapy, as a non-surgery therapy, was simple to operate, could be accepted by patients. Muscle-derived stem cells following injection have many advantages, such as long-term survival, not easy to broken down, not easy to move, low immunogenicity, and will have a bright prospect in the future.