Chinese Journal of Tissue Engineering Research ›› 2012, Vol. 16 ›› Issue (38): 7092-7095.doi: 10.3969/j.issn.2095-4344.2012.38.013

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Antibacterial property of a zinc-containing hydroxyapatite/titania hybrid coating

Zhang Jing-ying1, Sun Shen-xia1, Qi Min2, Ai Hong-jun3   

  1. 1School of Medicine, Dalian University, Dalian 116622, Liaoning Province, China
    2School of Materials Science and Engineering, Dalian University of Technology, Dalian 116024, Liaoning Province, China
    3School of Stomatology, China Medical University, Shenyang 110001, Liaoning Province, China
  • Received:2012-01-30 Revised:2012-02-23 Online:2012-09-16 Published:2012-09-16
  • About author:Zhang Jing-ying☆, Doctor, Lecturer, School of Medicine, Dalian University, Dalian 116622, Liaoning Province, China jingying78@ gmail.com

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Abstract:

BACKGROUND: The effective ways to improve the success rate of titanium implants are to improve the antibacterial properties of titanium implants and reduce the incidence of peri-implantitis.
OBJECTIVE: To investigate the antibacterial properties of the zinc-containing hydroxyapatite (ZnHA)/titania (TiO2) hybrid coating.
METHODS: First, a porous titania coating was produced on pure titanium (Ti) by micro-arc oxidation treatment. And then a ZnHA /TiO2 biological coating was prepared via sol-gel method. The concentration of Zn2+ release of Ti samples in each group was measured by inductively coupled plasma emission spectrometer. The adhesion number and morphologies of Porphyromonas gingivalis W83 implanted on the surface of hybrid coating were characterized by scanning electron microscope and bacteriostasis experiment.
RESULTS AND CONCLUSION: The concentration of Zn2+ release in the Tris buffer was increased with the Zn/Ca molar ratio in precursor solution increased. The growth of Porphyromonas gingivalis on the surface of ZnHA/TiO2 coating was inhibited obviously, and the form of Porphyromonas gingivalis adhered on the surface of coating had changed. These findings suggest that the ZnHA/TiO2 hybrid coatings on titanium implants have good antibacterial property.

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