Abstract:

BACKGROUND: Studies have demonstrated that the peak bone mass in women is lower than that in men, and value varies wildly in different regions, thus, it is necessary to measure peak bone mass values in each region.   
OBJECTIVE: To investigate the change laws of calcaneus bone density with age, body mass index (BMI) values and other variations of senior intellectual females in Shanghai.
METHODS: Totally 197 females were included and divided into 7 groups with 5-year intervals. The age, height, body weight, and calcaneus bone density of subjects were recorded. The correlation between peak bone mass and age, body weight or grasp force were analyzed by stepwise regression analysis.
RESULTS AND CONCLUSION: The results showed that the peak of calcaneus bone density of senior intellectual females in Shanghai appeared at 38-39 years. The decline rate of bone density values biggest dropped in 31-35 years and 41-45 years. Stepwise regression analysis showed the peak bone mass was positive to age, body weight or grasp force, especially age, which obviously affects peak bone mass. Low or early peak bone mass would result in high risk of osteoporosis. It is revealed that compared to normal women, the senior intellectual females are at greater risk of osteoporosis in Shanghai.