Chinese Journal of Tissue Engineering Research ›› 2012, Vol. 16 ›› Issue (28): 5281-5286.doi: 10.3969/j.issn.2095-4344.2012.28.031

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Resistance exercise effects on skeletal muscle hypertrophy

Wen An1, 2, Shi Qing-zhao3, Zhao Nan4   

  1. 1School of Graduate, Shanghai University of Sport, Shanghai 200438, China;
    2School of Physical Education, Xi’an University of Technology, Xi’an 710032, Shaanxi Province, China;
    3Health Care and Rehabilitation Department,
    4Sports School, Capital Institute of Physical Education, Beijing 100191, China
  • Received:2012-04-09 Revised:2012-04-23 Online:2012-07-08 Published:2012-07-08
  • About author:Wen An☆, Studying for doctorate, Associate professor, School of Graduate, Shanghai University of Sport, Shanghai 200438, China; School of Physical Education, Xi’an University of Technology, Xi’an 710032, Shaanxi Province, China awen0015@yahoo.com.cn

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Abstract:

BACKGROUND: Resistance exercise can promote muscle growth, resulting in skeletal muscle hypertrophy.
OBJECTIVE: To review the literature addressing the influence of resistance exercise on skeletal muscle by using cell biology and molecular biology method.
METHODS: PubMed (1999/2011-05) was electronically retrieved for articles related to resistance exercise effects on skeletal muscle hypertrophy, and then 45 articles were adopted by explicating inclusion and exclusion. The abstracts and the part of texts were obtained through the PubMed, and Springer or Sciencedirect was searched to get full texts so as to analyze the research progress of resistance exercise effects on skeletal muscle hypertrophy.
RESULTS AND CONCLUSION: The response of circulation assimilation hormones including growth hormone, insulin-like growth factor-1 and testosterone level change to resistance exercise and the internal environment factors have the significant effects on skeletal muscle hypertrophy. The cellular biological effects of resistance exercise on skeletal muscle are also further discussed. This field is focused on the methods of mammalian target of rapamycin mediating skeletal muscle protein synthesis, inflammation mechanism of prostaglandins and tumor necrosis factor α, and influence of tension-sensor to adding muscles after signal changing.

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