Novel Zero-P versus titanium plate with cage interbody fixation and fusion system in repairing cervical spondylosis: early stability

doi:10.3969/j.issn.2095-4344.2016.22.005

Abstract

Abstract:

BACKGROUND: It is notable to treat cervical spondylosis using the anterior cervical discectomy and fusion, but there are such complications as cervical instability and low fusion rate. Titanium plate with cage can solve those defects, while anterior unfamiliar matter and dysphagia appear. A new anterior cervical interbody fusion Zero-P with support and fixation function has been widely used in clinic.

OBJECTIVE: To analyze early stability in repairing cervical spondylosis using a new Zero-P interbody fixation and fusion system, and compare with a titanium plate with cage interbody fixation and fusion system.

METHODS: We retrospectively analyzed the clinical date of 31 patients with cervical spondylosis who underwent the anterior cervical discectomy and fusion in the Department of Orthopedics, Affiliated Hospital of Jiangsu University between August 2010 and August 2014. Fifteen patients were treated with a Zero-P implant (Zero-P group) and sixteen patients with a titanium plate with cage (cage group). We recorded operation time, intraoperative blood loss, preoperative and postoperative Visual Analogue Scale scores and Japanese Orthopedic Association scores, postoperative incidence of dysphagia and degeneration rate of adjacent joint.

RESULTS AND CONCLUSION: (1) Postoperative symptoms were apparently improved, without severe complications in both groups. (2) Operation time and intraoperative blood loss were better in the Zero-P group than in the cage group (P < 0.05). (3) Postoperative Visual Analogue Scale scores and Japanese Orthopedic Association scores were significantly improved in both groups (P < 0.05). The recovery rate of Japanese Orthopedic Association scores was similar between the two groups (81%, 81%; P > 0.05). (4) Mild dysphagia was experienced by one case (7%) in the Zero-P group, but nine cases (44%) in the cage group. Significant difference in the incidence of dysphagia was detected between the two groups after treatment (P=0.037). However, no significant difference in degeneration rate was detectable between the two groups (P=0.48). (5) These findings verify that in the anterior cervical discectomy and fusion, the new Zero-P and titanium plate with cage interbody fixation and fusion system are effective choices for cervical spondylosis. However, the Zero-P interbody fixation and fusion system showed a low incidence of postoperative dysphagia and better stability.

中国组织工程研究杂志出版内容重点：人工关节；骨植入物；脊柱；骨折；内固定；数字化骨科；组织工程

Key words: Spinal Fusion, Bone Transplantation, Deglutition Disorders, Tissue Engineering

CLC Number:

R318

Xu Yi-qi, Zhang Xue-song, Sun Tai-cun, Jing Dan-feng, Chen Hai-ning, Cui Xue-wen. Novel Zero-P versus titanium plate with cage interbody fixation and fusion system in repairing cervical spondylosis: early stability[J]. Chinese Journal of Tissue Engineering Research, 2016, 20(22): 3227-3234.

Figures/Tables 4

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