Preparation of porous nano-hydroxyapatite/polyamide composites for bone repair

doi:10.3969/j.issn.2095-4344.2016.03.016

Abstract

Abstract:

BACKGROUND: Compared with dense bone repair materials, porous materials has lower intensity, but its three-dimensional porous network structure can ensure a larger surface area that is more conducive to cell adhesion, growth and division as well as nutrient transmission.
OBJECTIVE: To investigate the preparation and performance of porous nano-hydroxyapatite/polyamide composites.
METHODS: Porous nano-hydroxyapatite/polyamide composites were prepared using chemical foaming method, and different composite bone repair materials were made by regulating foaming agent amount and nano-hydroxyapatite content. Mechanical properties, porosity and composition of the composite bone repair materials were detected.
RESULTS AND CONCLUSION: Porous nano-hydroxyapatite/polyamide composites were substantially tubular
channels, and had relatively good connectivity and uniform distribution, with a pore size of 260-400 μm, porosity of 35%-57%. Foaming agent amount, nano-hydroxyapatite content and density of composite materials all are influential factors of the total porosity. Porous nano-hydroxyapatite/polyamide composites have better mechanical properties and compressive strength than the cancellous bone, and the foaming agent has no influence on its shape, composition and diffraction peaks.

中国组织工程研究杂志出版内容重点：生物材料；骨生物材料; 口腔生物材料; 纳米材料; 缓释材料; 材料相容性；组织工程

Qiangbashanzeng, Liu Xiao-lan. Preparation of porous nano-hydroxyapatite/polyamide composites for bone repair[J]. Chinese Journal of Tissue Engineering Research, 2016, 20(3): 392-396.

Figures/Tables 5

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