Left ventricular volume and mitral annular motion under different occluders for atrial septal defect occlusion: an evaluation by real-time three-dimensional echocardiography

Abstract

Abstract:

BACKGROUND: Occluder closure of atrial septal defect exhibits clear function, safety and efficiency advantages
OBJECTIVE: Using real-time three-dimensional echocardiography (RT-3DE) technique to evaluate the effect of atrial septal defect occlusion using different occluders on left ventricular structure and motion of the mitral annulus.
METHODS: Thirty-seven cases diagnosed as atrial septal defect underwent atrial septal defect occlusion, including 20 males and 17 females, aged 20-60 years. The occluder was chosen individually according to defect size and edge hardness. Conventional and RT-3DE examinations were performed at 1 day prior to occlusion, 1 and 3 months after occlusion.
RESULTS AND CONCLUSION: Four of 37 patients were withdrawn from the study because of poor RT-3DE results. The other 33 patients harvested good occlusion results. At 1 and 3 months after occlusion, left ventricular end diastolic volume, left ventricular end systolic volume, left atrial end diastolic volume, left atrial end systolic volume were significantly increased (P < 0.05). Moreover, the more increase in these parameters occurred at 3 months after occlusion (P < 0.05). There were no significant changes in left ventricular ejection fraction and mitral annular displacement at three different time points. Left ventricular volume change rate and left atrial volume change rate were positively correlated to the type of occluders, while there was no correlation between endocardial cushion stump and mitral annular displacement. These findings suggest that atrial septal defect occlusion can increase the volume of the left ventricle and left atrium, but exhibit no effect on the motion of the mitral annulus.

中国组织工程研究杂志出版内容重点：生物材料；骨生物材料; 口腔生物材料; 纳米材料; 缓释材料; 材料相容性；组织工程

全文链接：

Key words: heart septal defects, atrial, septal occluder device, echocardiography, stress

CLC Number:

R318

Xiapuhaiti Adili, Wu Zhi-sheng, Mu Yu-ming, Tang Qi, Tang Sha. Left ventricular volume and mitral annular motion under different occluders for atrial septal defect occlusion: an evaluation by real-time three-dimensional echocardiography[J]. Chinese Journal of Tissue Engineering Research, 2014, 18(43): 7001-7006.

Figures/Tables 2

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