Chinese Journal of Tissue Engineering Research ›› 2012, Vol. 16 ›› Issue (42): 7961-7964.doi: 10.3969/j.issn.2095-4344.2012.42.033

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Research progress in animal models of chronic bronchitis

Zheng Qiu-ju, Tan Jing, Yang Ren-da   

  1. Acupuncture and Massage College, Hunan University of Traditional Chinese Medicine, Changsha 410208, Hunan Province, China
  • Received:2012-01-09 Revised:2012-02-11 Online:2012-10-14 Published:2012-10-14
  • Contact: Yang Ren-da, Professor, Acupuncture and Massage College, Hunan University of Traditional Chinese Medicine, Changsha 410208, Hunan Province, China yangrd11@163.com
  • About author:Zheng Qiu-ju★, Studying for master’s degree, Acupuncture and Massage College, Hunan University of Traditional Chinese Medicine, Changsha 410208, Hunan Province, China zqj7158261@163.com

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Abstract:

BACKGROUND: In recent years, many scholars have done a lot of studies on pathological features of chronic bronchitis based on animal model construction to further elucidate the genetic background of the incidence, predisposing factors, and pathogenesis.
OBJECTIVE: To summarize the investigative situation and progression about animal models of chronic bronchitis at home and abroad.
METHODS: Databases of CNKI and PubMed (1999-01/2011-10) were searched to retrieve the related articles about animal models of chronic bronchitis using the key words of “chronic bronchitis, animals, model” in Chinese and English, respectively. Finally, 24 articles were included in result analysis.
RESULTS AND CONCLUSION: The methods to construct an animal model of chronic bronchitis mainly include chemical medicine, bacterial infection, passive smoking and composite method. Each method has its own advantages and disadvantages. Up to now, there is no recognized ideal method that needs further studies.

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