Chinese Journal of Tissue Engineering Research ›› 2012, Vol. 16 ›› Issue (39): 7317-7321.doi: 10.3969/j.issn.2095-4344.2012.39.021

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Progress of magnesium ions and magnesium alloy implant application in the clinical orthopaedics

Xie Xing-wen1, Huang Jin2, Li Ning2, Xu Wei3, Hu Bin2, Xu Shi-hong2   

  1. 1Institute of Traditional Chinese Medicine of Gansu Province, Lanzhou 730050, Gansu Province, China
    2Gansu Provincial Hospital of Traditional Chinese Medicine Lanzhou 730000, Gansu Province, China
    3Gansu College of Traditional Chinese Medicine Lanzhou 730050, Gansu Province, China
  • Received:2011-12-17 Revised:2012-01-19 Online:2012-09-23 Published:2012-09-23
  • Contact: Xie Xing-wen, Doctor, Master’s supervisor, Associate chief physician, Institute of Traditional Chinese Medicine of Gansu Province, Lanzhou 730050, Gansu Province, China 827975272@qq.com
  • About author:Xie Xing-wen☆, Doctor, Associate chief physician, Institute of Traditional Chinese Medicine of Gansu Province, Lanzhou 730050, Gansu Province, China 827975272@qq.com

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Abstract:

BACKGROUND: Magnesium ions are constant element, can be absorbed by the body and have obvious advantages as medical biomaterials.
OBJECTIVE: To summarize the advantages, disadvantages, and research progress of magnesium ions and magnesium alloys application in orthopedics in recent years.
METHODS: PubMed database and CNKI database were used to search the articles published from 2000 to 2011 on the progress of magnesium ions and magnesium alloys application in medical field.
RESULTS AND CONCLUSION: The traditional medical metal materials including stainless steel, cobalt-based alloy and titanium based alloys which have the disadvantages of poor biocompatibility, un-matched biomechanical properties and the second surgery, and other defects. Magnesium alloys have good biomechanical compatibility, biodegradable performance, bio-security and rich resource. Magnesium alloys have the characteristics of degradation through the corrosion under physiological electrolyte environment and show a great application potential in the orthopedics field.

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