Chinese Journal of Tissue Engineering Research ›› 2011, Vol. 15 ›› Issue (4): 597-601.doi: 10.3969/j.issn.1673-8225.2011.04.007

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Comparison of two anterior decompression bone fusion treatments plus titanium plate implantation for two-level cervical spondylotic myelopathy

Liu Yong, Chen Liang, Gu Yong, Xu Yun, Yang Hui-lin, Tang Tian-si   

  1. Department of Orthopaedic Surgery, First Affiliated Hospital of Soochow University, Suzhou 215006, Jiangsu Province, China
  • Received:2010-08-19 Revised:2010-10-27 Online:2011-01-22 Published:2011-01-22
  • Contact: Chen Liang, Doctor, Chief physician, Professor, Department of Orthopaedic Surgery, First Affiliated Hospital of Soochow University, Suzhou 215006, Jiangsu Province, China chenliang1972@sina.com
  • About author:Liu Yong★, Studying for master’s degree, Department of Orthopaedic Surgery, First Affiliated Hospital of Soochow University, Suzhou 215006, Jiangsu Province, China liuyong4034554@ sina.com

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Abstract:

BACKGROUND: Anterior surgical approaches for cervical spondylotic myelopathy (CSM) include Cloward method, anterior cervical discectomy and fusion or anterior cervical corpectomy and fusion.
OBJECTIVE: To compare the clinical effects and biocompatibility of two different anterior approaches in combination with titanium plate implantation for two-level CSM.
METHODS: A total of 54 cases of two-level CSM were randomly divided into two groups: 27 cases were treated with anterior cervical discectomy and fusion (ACDF), and 27 with anterior cervical corpectomy and fusion (ACCF). Complications, the function recovery rate of spinal cord, the height and Cobb’s angle of the fused segment between two groups.
RESULTS AND CONCLUSION: Four patients in ACDF group and four in ACCF group were excluded for analysis because of follow-up lost or follow-up less than 2 years. The follow-up period of 23 patients in ACDF group was 26-48 months and of 23 patients in ACCF group was 24-53 months. There were no significant differences in hospital stay, the height of the fused segment, complications, or the function recovery rate of spinal cord between the two groups (P > 0.05). Operation time and bleeding amount were significantly greater in ACCF group compared with ACDF group (P < 0.05). Postoperative Cobb’s angle of the fused segment was significantly better in the ACDF group (P < 0.05), and incidence of complications was low in bone donor region (P < 0.05). Results show that surgical managements of two-level CSM using ACCF or ACDF obtained favorable clinical outcomes. However, ACDF was superior over ACCF in terms of operation time and bleeding amount, Cobb’s angle of the fused segment, vertebral bone reservation, elimination of donor site complications.

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