Chinese Journal of Tissue Engineering Research ›› 2010, Vol. 14 ›› Issue (31): 5853-5855.doi: 10.3969/j.issn.1673-8225.2010.31.038

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Flow measurement of in situ and free-state left internal mammary artery in patients undergoing coronary artery bypass grafting

Song Zheng, Li De-cai, Liu Chun-xiao, Zhang Hai-zhou, Zhang Wen-long, Wang Zheng-jun, Zi Jie   

  1. Department of Cardiovascular Surgery, Provincial Hospital Affiliated to Shandong University, Jinan  250021, Shandong Province, China
  • Online:2010-07-30 Published:2010-07-30
  • Contact: Li De-cai, Associate professor, Department of Cardiovascular Surgery, Provincial Hospital Affiliated to Shandong University, Jinan 250021, Shandong Province, China decaili@hotmail.com
  • About author:Song Zheng★, Studying for master’s degree, Department of Cardiovascular Surgery, Provincial Hospital Affiliated to Shandong University, Jinan 250021, Shandong Province, China szhaijie@sina.com

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Abstract:

BACKGROUND: Left internal mammary artery (LIMA) bypass graft has become first choice and standard technique for coronary artery disease, which has reliable efficacy and long-term patency. However, the question whether sequential anastomosis is appropriate to LIMA and the sequential vessel blood flow is adequate for human body remains controversial.
OBJECTIVE: To explore the differences in blood flow between in situ and free state of LIMA in patients with the coronary artery disease (CAD) undergoing off-pump coronary artery bypass grafting.
METHODS: Between March 2008 and March 2009, 56 patients with CAD who had undergone off-pump coronary artery bypass grafting with LIMA bypass grafts were selected. A pedicle-free smooth segment of proximal LIMA was dissociated during surgery. LIMA’s in situ blood flow was measured when the hemodynamics stabilized. When the branch of LIMA was completely dissociated, the free state blood flow was measured.
RESULTS AND CONCLUSION: The in situ mean flow of 56 patients was significantly better than free state flow [(32.0±5.0), (10.0±1.2) mL/min, P < 0.01]. Results show that the blood flow of LIMA is related with the number of branching vessel and the LIMA has the ability of flow reservation, which provides theoretical evidence for coronary artery bypass grafting sequential anastomosis.

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