Low-frequency pulsed electromagnetic fields for treatment of osteoporosis

doi:10.3969/j.issn.2095-4344.2016.08.022

Abstract

Abstract:

BACKGROUND: The most commonly used physiotherapies for osteoporosis include low-frequency pulsed electromagnetic field, ultrashort wave therapy, and extracorporeal shock wave therapy. Because of the uncertain intensity of extracorporeal shock wave and uncertain efficacy of ultrasound therapy, low-frequency pulsed electromagnetic fields have become the most widely used treatment for osteoporosis in clinic.
OBJECTIVE: To review the mechanism and clinical application of low-frequency pulsed electromagnetic fields in the treatment of osteoporosis.
METHODS: A computer search by the first author of PubMed and CNKI databases was performed for relevant articles using the keywords of “pulsed electromagnetic fields and osteoporosis” or “osteoblast or osteoclast” in English and “osteoporosis; pulsed pulsed electromagnetic fields; osteoblasts; osteoclasts” in Chinese, respectively. After initial search, there were 169 articles, and according to the inclusion criteria, 29 highly relevant articles that are authentic and have clear views were analyzed.
RESULTS AND CONCLUSION: The pulsed electromagnetic field as a non-drug therapy is characterized by no trauma, no infection, simple operation, low cost, long-term use, and good safety. Its efficacy has been increasingly affirmed by researchers and clinicians. Pulsed electromagnetic fields can promote the synthesis of DNA, influence the proliferation and differentiation of osteoblasts, increase the apoptosis of osteoclasts, and have a certain window effect. Pulsed electromagnetic fields can effectively relieve pain and increase bone density level in patients with osteoporosis, which can increase its efficacy in combination with other drugs and have a wide range of clinical applications.

中国组织工程研究杂志出版内容重点：生物材料；骨生物材料; 口腔生物材料; 纳米材料; 缓释材料; 材料相容性；组织工程

Zhao Lin. Low-frequency pulsed electromagnetic fields for treatment of osteoporosis[J]. Chinese Journal of Tissue Engineering Research, 2016, 20(8): 1210-1216.

Figures/Tables 2

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