Bone fusion and fixation in the repair of lumbar brucellar spondylitis: spinal stability in 6-month follow-up

doi:10.3969/j.issn.2095-4344.2015.09.013

Abstract

Abstract:

BACKGROUND: After simple debridement and fusion of brucella spondylitis, bed time is long. Activities are likely to cause spinal instability. Bone nonunion rate is very high, and the curative effects are poor.
OBJECTIVE: To investigate the efficacy of debridement and interbody fusion fixation for repair of lumbar brucellar spondylitis and for stable spine structure.
METHODS: A total of 31 cases of lumbar brucellar spondylitis were obtained from Affiliated Hospital of Chinese Medicine, Xinjiang Medical University between January 2007 to August 2013, including 22 males and 9 females, at the age of 42-73 years, averagely 52 years. Their course of disease was 3-13 months, averagely 5 months. All patients were administered combination therapy of rifampin and minocycline and streptomycin, and then received one-stage debridement and fusion, spinal pedicle screw fixation system. Japanese Orthopaedic Association scores were compared before and after the surgery for assessing prognosis and functional recovery. Bone fusion was observed using X-ray during follow-up.
RESULTS AND CONCLUSION: All patients were followed up for 6-24 months, averagely 12.6 months. After repair, Japanese Orthopaedic Association scores were increased, showing significant differences compared with pre-treatment (P < 0.05). No recurrence or severe complications appeared during follow-up. All patients were rechecked using X-ray within 5 days after repair. Results showed that the internal fixation and bone graft fusion were good. Final follow-up radiographs revealed that bone healing was good, and the spine was stable. Above data confirmed that on the basis of triple-drug therapy, debridement and interbody fusion and internal fixation for treating lumbar brucellar spondylitis can maintain spinal stability, reduce complications, and obtain reliable repair effects.

中国组织工程研究杂志出版内容重点：人工关节；骨植入物；脊柱；骨折；内固定；数字化骨科；组织工程

全文链接：

Key words: Brucellosis, Spondylitis, Bone Transplantation

CLC Number:

R318

Niu Guang-xu, Kahaer•Aikenmu, Zhao Jiang, Chu Ge, Wang Zhen-bin, Gu Wen-fei, Tu Lai-yong. Bone fusion and fixation in the repair of lumbar brucellar spondylitis: spinal stability in 6-month follow-up[J]. Chinese Journal of Tissue Engineering Research, 2015, 19(9): 1388-1392.

Figures/Tables 1

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