Percutaneous vertebroplasty for the treatment of osteoporotic vertebral compression fractures with different fracture periods

doi:10.3969/j.issn.2095-4344.2013.21.005

Abstract

Abstract:

BACKGROUND: In recent years, the technique of percutaneous vertebroplasty for the treatment of osteoporotic vertebral compression fractures is gradually developed, but there is a controversy of the clinical effectiveness of percutaneous vertebroplasty for the treatment of osteoporotic vertebral compression fractures with different fracture periods.
OBJECTIVE: To compare the effectiveness of percutaneous vertebroplasty for the treatment of osteoporotic vertebral compression fractures with different fracture periods
METHODS: A retrospective study was conducted to review 91 cases receiving percutaneous vertebroplasty on 127 vertebral compression fractures. The patients were divided into three groups according to the time from fracture or pain occurrence to surgery: < 3 weeks group, 3 weeks-6 months group, ≥ 6 months group. The visual analogue scale, the Activity of Daily Living Scale and the height of vertebras were recorded and analyzed in the three groups.
RESULTS AND CONCLUSION: (1) Pain was relieved significantly in the three groups with time going (P < 0.01). The pain relief was superior in the < 3 weeks group and 3 weeks-6 months group as compared with ≥ 6 months group (P < 0.01), but there was no difference between the former two groups. (2) Scores on the Activity of Daily Living Scale were all increased in the three groups after treatment, and gradually increased with time going (P < 0.01). The scores in the three groups were ranked from top to bottom as follows: < 3 weeks group, 3 weeks- 6 months group, and ≥ 6 months group (P < 0.01). (3) No difference in anterior and middle vertebral height was found among the three groups before treatment. At 3 days after treatment, the anterior and middle vertebral height was arranged from top to bottom as follows: 3 weeks group, 3 weeks-6 months group, and ≥ 6 months group (P < 0.01). There was no difference in the posterior vertebral height among three groups prior to treatment and at 3 days after treatment. Results show that the clinical effectiveness of percutaneous vertebroplasty for the treatment of osteoporotic vertebral compression fractures more than 6 months is worse.

Key words: biomaterials, tissue-engineered bone materials, percutaneous vertebroplasty, bone cement, osteoporotic vertebral compression fractures, pain, activity of daily living, anterior vertebral body, vertebral height

CLC Number:

R318

Zhang Qi-liang1, Wang Jun2, Lin Yong1. Percutaneous vertebroplasty for the treatment of osteoporotic vertebral compression fractures with different fracture periods[J]. Chinese Journal of Tissue Engineering Research, doi: 10.3969/j.issn.2095-4344.2013.21.005.

Figures/Tables 4

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