Abstract:

BACKGROUND: With the advances in surgical techniques, especially the promotion of scoliosis operation, the bone graft material has put forward higher requirements. Bone grafting material should not only have osteogenic activity, but also display similar characteristic on the structure and mechanical properties of natural bone, and meet the biomechanical requirements.
OBJECTIVE: To review the application progresses of new-type bone graft materials in scoliosis correction and fusion.
METHODS: Elsevier full-text database was retrieved by computer for relevant articles (2009-2012) with the key words of “non-hydroxyapatite, hydroxyapatite, scoliosis” in English. At the same time the HowNet and China Journal Full-text databases were searched for relevant articles with the key words of “scoliosis, bone graft material, nano artificial bone, bone morphogenetic protein 2, artificial bone” in Chinese. Totally 27 articles were included.
RESULTS AND CONCLUSION: Nano artificial bone has excellent biocompatibility and bone conduction. It imitates the component and structure characteristic of natural bone. Besides, its structure is basically the same with the natural bone crystals part to provide a microenvironment which is similar to natural bone. In spine surgery, bony fusion is a marker of successful treatment of scoliosis surgery. However, spine surgeons have been puzzled by the source of bone graft materials. So the hot spots at home and abroad are looking for bone repair materials that cannot only form bone fusion but also have osteogenic activity. Nano artificial bone shows a broad prospect in the application of spinal surgery.