Abstract:

BACKGROUND: Determination of fractional exhaled nitric oxide (FENO) can directly reflect airway inflammation. It is noninvasive, reproducible, rapid, and has good dependence in patients.
OBJECTIVE: To investigate FENO normal value in healthy people.
METHODS: Totally 101 different-age healthy people were measured EFNO with the NIOX Exhaled Nitric Oxide Monitoring System. Pulmonary ventilation function and allergen-IgE were measured.
RESULTS AND CONCLUSION: A total of 101 healthy people’s FENO value was (5-58)×10^-9. Average FENO value was 18.119×10^-9, and normal range was (7.674-28.564)×10^-9. Lower FENO value was found in female compared with male. The mean value in 51 female was 14.901×10^-9, and that in 50 male people was 21.400×10^-9. FENO value had no significant correlation with ages. The mean value in 20 to 29 years old and 60 to 80 years old health people was lower than 18.119×10^-9, and that of 40 to 59 years old people was 21.3×10^-9 that was highest. There was significant correlation in FENO value between gender and height. These results suggest that the FENO values of these101 healthy people were slightly higher than those of international reference value, which have significant correlation between gender and height.