Abstract:

BACKGROUND: Studies have shown that the collagen fiber orientation is closely related with meridian, and there are at least two collagen fibers in each cell in order to stay connection with each other, so scholars have speculated that it is the human energy transfer signaling pathway.
OBJECTIVE: To observe the effect of collagen fibers signal changes in the recovery of the skeletal muscle injury based on the meridian collagen pathway hypothesis, and to prove that the interference effect of electroacupuncture on collagen signal is the basic mechanism to promote skeletal muscle repair.
METHODS: Male Sprague Dawley rats were randomly divided into three groups: the control group was the blank control; the model group was used to establish the skeletal muscle injury model by weight combat method; rats in the treatment group received the G6850 electric acupuncture at Zusanli (ST36).
RESULTS AND CONCLUSION: The expression of collagenⅠfiber mRNA and hydroxyproline level in the treatment group were lower than those in the control group (P < 0.05), and the change trend was more stable in the treatment group when compared with the model group; the serum creatine kinase level in the treatment group reached to the normal level at 7 days after treatment, and there was a positive correlation between the changes of collagenⅠfibers and the serum creatine kinase level in the treatment group. The collagenⅠfibers and hydroxyproline level in the acupoint area after acupuncture may play a key role in the repair of muscle injury, thereby guiding the transmission and conversion process of acupuncture signal, and signal propagation always positively correlates with creatine kinase level during skeletal muscle repair.