Chinese Journal of Tissue Engineering Research ›› 2012, Vol. 16 ›› Issue (37): 6967-6972.doi: 10.3969/j.issn.2095-4344.2012.37.026

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Association of left ventricular geometry with left atrial volume and left ventricular volume in essential hypertensive elderly patients

Wang Zhi-feng1, Ma Yun2, Ren Rong2, Xu Xin-juan3   

  1. 1Department of Geriatrics & Hypertension, 2Department of Nephrology, the Fifth Affiliated Hospital of Xinjiang Medical University, Urumqi 830011, Xinjiang Uygur Autonomous Region, China; 3Department of Hypertension, the First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, Xinjiang Uygur Autonomous Region, China
  • Received:2012-06-09 Revised:2012-07-26 Online:2012-09-09 Published:2012-09-09
  • Contact: Xu Xin-juan, Professor, Chief physician, Doctoral supervisor, Department of Hypertension, the First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, Xinjiang Uygur Autonomous Region, China zcxu@medmail.com.cn
  • About author:Wang Zhi-feng★, Master, Associate chief physician, Department of Geriatrics & Hypertension, the Fifth Affiliated Hospital of Xinjiang Medical University, Urumqi 830011, Xinjiang Uygur Autonomous Region, China wzfshys@hotmail.com

Abstract:

BACKGROUND: Studies have shown that left atrial volume may embody left ventricular filling pressure, atrial structural remodeling and neurohormonal activity. Moreover, left atrial volume expansion is a strong predictor of poor prognosis following chronic heart failure.
OBJECTIVE: To study the changes of left atrial volume and left ventricular volume in elderly essential hypertension patients based on different left ventricular geometries.
METHODS: The left atrial volume and left ventricular volume of 129 essential hypertension elderly patients and 125 control subjects were measured with echocardiography and their differences were analyzed. The left ventricular geometries were classified according to Ganau standard. The essential hypertension group underwent ambulatory blood pressure monitoring in order to grouping comparison based on types of blood pressure rhythm.
RESULTS AND CONCLUSION: The left atrial volume, left atrial volume index, end-systolic left ventricular volume, end-diastolic left ventricular volume of the essential hypertension group compared with the control group were increased, and the difference was statistically significant (P < 0.05). In the essential hypertension group, duration of hypertension and rhythm of blood pressure could influence distribution of left ventricular geometries. The left atrial volume, left atrial volume index, end-systolic left ventricular volume, end-diastolic left ventricular volume of the abnormal geometries group compared with the normal geometries group were increased, significantly (P < 0.05). In essential hypertension elderly patients, the disease course and non-dipper blood pressure rhythm have important influence on left ventricular geometry; the left atrial volume and left ventricular volume are changed with different left ventricular geometries.

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