Chinese Journal of Tissue Engineering Research ›› 2012, Vol. 16 ›› Issue (34): 6457-6460.doi: 10.3969/j.issn.2095-4344.2012.34.037

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Detection and assessment of serum nickel and chromium levels in patients before and after the removal of the nickel-chromium alloy porcelain-fused-to-metal restoration

Guo Da-wei1, Teng Min-hua2, Chen Zheng-gang1, Zhai Jun-jiang2, Wen Cai2, Tian Ai2, Sun Ning-yuan2, Liang Xing2   

  1. 1Department of Stomatology, Qingdao Municipal Hospital, Qingdao 266071, Shandong Province, China;
    2Department of Prosthodontics, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, Sichuan Province, China
  • Received:2012-01-17 Revised:2012-03-13 Online:2012-08-19 Published:2012-08-19
  • Contact: Liang Xing, Doctoral supervisor, Professor, Chief physician, Department of Prosthodontics, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, Sichuan Province, China tengminhua@ 163.com
  • About author:Guo Da-wei☆, Doctor, Attending physician, Department of Stomatology, Qingdao Municipal Hospital, Qingdao 266071, Shandong Province, China gdavy@126.com

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Abstract:

BACKGROUND: Currently, there are few reports on whether the nickel-chromium alloy porcelain-fused-to-metal (PFM) restoration has a systematic effect on the human body.
OBJECTIVE: To investigate the clinical security of the nickel-chromium alloy PFM, according to the assessment of the serum levels of nickel and chromium before and after the removal of the restoration.
METHODS: Sixty-nine patients were selected for the study, who suspected that nickel-chromium alloy PFM could affect their health and therefore came to hospital to ask for removal of the crown. The serum levels of nickel and chromium in these 69 patients were detected before and 1 month after the removal of the nickel-chromium alloy PFM restorations. In addition, the serum levels of nickel and chromium in these patients were analyzed according to their age, gender, the number and duration of PFM restorations, and whether the metal was exposed or not in restoration.
RESULTS AND CONCLUSION: There were no statistical differences between the serum levels of nickel and chromium in patients before and after the removal of the nickel-chromium alloy PFM restoration (P > 0.05). In addition, the serum levels of nickel and chromium in patients had nothing to do with gender, age, the number and duration of PFM restorations, and whether the metal was exposed or not in restoration (P > 0.05 ). The amount of nickel and chromium released from nickel-chromium alloy PFM is small, which cannot affect the serum levels of nickel and chromium in the human body.

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