Abstract:

BACKGROUND: Long-term bed results in pressure sore. How to promote the wound healing and shorten the healing time are the essential parts of pressure sore treatment.
OBJECTIVE: To observe the influence of insulin on the treatment of pressure score wounds using bovine basic fibroblast growth factors.
METHODS: The 34 patients (45 pressure sores) of Sichuan Nanchong Central Hospital were divided into the experimental group and control group. In the control group, all the pressure sore wounds were external applied with wet pledget containing basic fibroblast growth factor (1-3 mL) and physiological saline (3-5 mL) after treated with TDP physiotherapy, while the experimental group was treated with the same process except the addition of insulin. The significant condition and wound healing time were recorded in two groups after 2 weeks, and the results were contrastive analyzed.
RESULTS AND CONCLUSION: Efficiency of experimental group was greater than the control group obviously (P < 0.05). But there was no significant difference between two groups in blood glucose concentration before treatment (P > 0.05). The addition of insulin can promote the healing of pressure sores, without the change of blood glucose levels of patients.