Chinese Journal of Tissue Engineering Research ›› 2011, Vol. 15 ›› Issue (7): 1150-1154.doi: 10.3969/j.issn.1673-8225.2011.07.003

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Construction of repair tendon-bone models in rabbits with postoperatibe acute rotator cuff rupture under stress and imaging evaluation during repairing

Li Sen1, Jin An-min2, Min Shao-xiong2, Zhang Hui2, Wang Qing1   

  1. 1 Department of Spinal Orthopaedics, Affiliated Hospital of Luzhou Medical College, Luzhou 646000, Sichuan Province, China
    2Orthopedics Center of Zhujiang Hospital, Southern Medical University, Guangzhou  510282, Guangdong Province, China
  • Received:2010-08-07 Revised:2010-12-03 Online:2011-02-12 Published:2011-02-12
  • Contact: Wang Qing, Professor, Chief physician, Master’s supervisor, Department of Spinal Orthopaedics, Affiliated Hospital of Luzhou Medical College, Luzhou 646000, Sichuan Province, China wqspine2004@163. com Jin An-min, Chief physician, Professor, Doctoral supervisor, Orthopedics Center of Zhujiang Hospital, Southern Medical University, Guangzhou 510282, Guangdong Province, China Jinanmin2008@163.com
  • About author:Li Sen☆, Doctor, Attending physician, Department of Spinal Orthopaedics, Affiliated Hospital of Luzhou Medical College, Luzhou 646000, Sichuan Province, China jht187@163.com
  • Supported by:

    the Natural Science Foundation of Luzhou Medical College, No. 2010108-64*

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Abstract:

BACKGROUND: Though many kinds of animals were used as models in the experiment of rotator cuff injury under stress, yet there is no single can be as the standard experimental animal model.
OBJECTIVE: To construct repair tendon-bone models of rabbits with acute rotator cuff rupture under stress and to evaluate the iconography in repairing.
METHODS: New Zealand white rabbits were underwent transverse myotenotomy of supraspinatus tendon and tendon insertion site reconstruction. After surgery, all animals were randomly divided into the stress and non-stress groups. Rabbits in the non-stress group were raise in normal cage, and those in the stress group were trained passive flexion and extension at 2 weeks after the reconstruction of the supraspinatus tendon. MRI and ultrasound examination was performed at the 2, 4 and 8 weeks after operation. 
RESULTS AND CONCLUSION: MRI test results: T2WI showed that the areas of the low signals of the tissues connected tendon and bone were larger and the signals of synovial fluid reduced more visible in stress group than in non-stress group at 4 and 8 weeks after operation. Ultrasound examination results: the continuous echoes appeared at the site of the rabbit supraspinatus tendon-bone in 2 groups, which showed more obvious in stress group than in non-stress group at 4 and 8 weeks after operation. The findings demonstrated that, repair tendon-bone models of rabbits with postoperatibe acute rotator cuff rupture under stress are successful constructed, and certain stress can promote repairing of the tendon-bone of rotator cuff.

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