Chinese Journal of Tissue Engineering Research ›› 2011, Vol. 15 ›› Issue (2): 347-350.doi: 10.3969/j.issn.1673-8225.2011.02.039

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Membrane proteins of the triad junction and excitation-contraction coupling in skeletal muscles

Ma Guo-zhen1, Li Wen-hui2, Luo Shuo3, Ma Yan-fen3   

  1. 1Department of Physical Education, Hebei University, Baoding  071000, Hebei Province, China
    2College of Sport Science, Hebei Normal University, Shijiazhuang  050016, Hebei Province, China
    3Health Care Hospital for Women and Children of Hebei Province, Baoding  071000, Hebei Province, China
  • Received:2010-10-08 Revised:2010-12-09 Online:2011-01-08 Published:2011-01-08
  • Contact: Li Wen-hui, Studying for master’s degree, College of Sport Science, Hebei Normal University, Shijiazhuang 050016, Hebei Province, China liwenhui3061563@163.com
  • About author:Ma Guo-zhen, Lecturer, Department of Physical Education, Hebei University, Baoding 071000, Hebei Province, China 997448708@qq.com

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Abstract:

BACKGROUND: The mechanism of excitation-contraction coupling (E-C coupling) in skeletal muscles and a fast and responsive E-C coupling mechanism directly determine the motor ability. The triad junction, which is the specific structure in skeletal muscles, is the infrastructures of E-C coupling. The membrane proteins in the triads play a key role in the development of the triads, maintaining the normal structural form of the triads and exerting the triadic full functions.
OBJECTIVE: To review the research advances of triadic membrane proteins and to summarize the structure and functions of dihydropyridine receptor (DHPR), ryanodine receptor, MG29 protein, JP protein, Calumin and STIM1 protein, calsequestrin and TRIC.
METHODS: Papers regarding skeletal muscle senescence and power-velocity were searched by computer in databases of CNKI, Duxiu, Elsevier SD and Springer Link from 1980 to 2010. The change laws of skeletal muscle power-velocity with aging and effect of this law on muscle was analyzed. 
RESULTS AND CONCLUSION: Totally 28 documents were included in this paper. Literature summary showed that, DHPR, ryanodine receptor, MG29 protein, JP protein, Calumin and STIM1 protein, calsequestrin and TRIC doing its own job in skeletal muscles, all of them play an indispensable role in maintaining normal function of skeletal muscles. However, the study of these proteins remains limited, which need further exploration.

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