Abstract:

BACKGROUND: Isocitrate dehydrogenase (IDH) and succinic dehydrogenase (SDH) play key role in aerobic oxidation. However, reports about the effects of different training models and training periods on the activity of IDH and SDH in skeletal muscle have little coverage.
OBJECTIVE: To observe the effects of different training on the activity of IDH and SDH in rat skeletal muscles. 
METHODS: According to BEDFORD TG standards, aerobic exercise, anaerobic exercise and aerobic and anaerobic cross-training motion models were established using treadmill running at different work intensities. Rats in control group lived in the cages quietly, and all the animals were killed immediately when the exercise training completed. Then the activity of IDH and SDH were determined by ultraviolet spectrophotometer.
RESULTS AND CONCLUSION: The activity of IDH and SDH were obviously increased at 4 and 6 weeks after treadmill training (P < 0.05). To the cross-training group, they increased after 2 weeks’ training (P < 0.05), however, the activity of IDH and SDH decreased at 4 and 6 weeks after aerobic exercise training (P< 0.05). While to anaerobic exercise group, the activity of IDH and SDH had no significant differences. The present findings demonstrated that, long-time aerobic exercise and short-time aerobic and anaerobic cross-training can protect the activity of IDH and SDH.