Abstract:

OBJECTIVE: To evaluate biomechanics characteristics of acute knee ligament injury, to classify and summarize the treatment mechanism and means of rehabilitation for anterior cruciate ligament injury and after the intervention of artificial biomaterials.
METHODS: An online search of Wanfang database from January 1996 to October 2010 was performed for articles related to the application of biomaterials for anterior cruciate ligament repair, with key words of “tissue engineering, knee joint, ligament, biomaterials” in Chinese.
RESULTS: The knee joint is an important joint for human movement and weight-bearing, also an important landing buffer device, due to several internal and external factors during the movement result in anterior cruciate ligament injury. Tissue engineering artificial ligament is the current research focus, a lot of researches investigate the selection and construction of scaffold materials, the methods of seed cells isolation and culture, cytokine and surface modification. At present, there are increasingly developed and various means of rehabilitation for anterior and posterior cruciate ligament using artificial materials, but they often have their advantages and disadvantages.
CONCLUSION: Although artificial ligament has deficiencies and is not an ideal graft to completely replace the ligament, the artificial ligament serves as an option for anterior cruciate ligament reconstruction, it is an important progress in the history of anterior cruciate ligament reconstruction, in particular, it is necessary to select appropriate individual rehabilitation among various biological means of rehabilitation with the advantages and disadvantages.