Abstract:

BACKGROUND: TiO₂ film containing SrFe12O19 magnetic powder is coated on the surface of NiTi alloy and 316L stainless with sol-gel method. After magnetization, micromagnetic field is established on it. Dynamic clotting time of 316L stainless steel and NiTi alloy can be increased with TiO2 film containing SrFe12O19, and hemolysis rate is decreased, which indicate the improved blood compatibility of TiO2 film contained SrFe12O19.
OBJECTIVE: To discuss mechanism of the interaction between micromagnetic field and blood.
METHODS: SrFe12O19 nano-powder was prepared by the method of harnessing the citric acid, its morphology and size were studied by using X-ray diffraction and scanning electron microscopy. The magnetic properties were detected by using a magnetometer. The sol-gel method was used to prepare the TiO₂ film containing SrFe12O19 powder, and the coating film component was then characterized by X-ray diffraction. The relations between the micro-magnetic field surface and the blood compatibility of materials were evaluated by dynamic clotting time and hemolysis rate.
RESULTS AND CONCLUSION: Adsorptions of Ca ^₂₊ , fibrinogen, platelets and erythrocytes in blood on material surface were prevented because of their diamagnetism. So the process of clotting was restrained, which indicated an antithrombotic effect and the improved blood compatibility of materials.