Abstract:

BACKGROUND: Heat shock protein 72 expression in skeletal muscle cells induced by exercise stress has correlated with muscular injury.
OBJECTIVE: To summarize the correlation between heat shock protein 72 expression in skeletal muscle cells and exercise, and to explore the potential value in sports medicine.
METHODS: A computer-based online search was conducted in National Scientific & Technical Library Document Center with the key words of “heat shock protein 72, skeletal muscle” in both Chinese and English from January 1990 to October 2009. Relevant data were also searched in Wanfang database with the key word of heat shock protein 72 in Chinese from January 1994 to October 2009. Articles addressing originality, reliability, identification, general analysis, and high correlation were included; however, articles due to unconscionable design and unclear review were excluded.
RESULTS AND CONCLUSION: The heat shock protein existed in the organism widely and had protective function on body. Exercise stress which induced heat shock protein 72 mRNA expression and heat shock protein 72 synthesis was highly correlated with exercise loading dose, intension, and duration, in particular exercise intension. When heat shock protein 72 was strongly stimulated by exercise stress, the synthetic dose was increased significantly. As a muscle stress indicator, heat shock protein 72 provided important evidence for functional changes of skeletal muscle cells induced by exercise; on the other hand, it was also an ideal indicator for preventing overtraining and training plan.