Chinese Journal of Tissue Engineering Research ›› 2016, Vol. 20 ›› Issue (8): 1069-1074.doi: 10.3969/j.Issn.2095-4344.2016.08.001

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Percutaneous vertebroplasty with high-viscosity bone cement treats Kümmell disease

Zhang Liang, Feng Xin-min, Wang Jing-cheng, Tao Yu-ping, Yang Jian-dong, Zhang Sheng-fei, Huang Ji-jun, Cai Jun, Zhang Zhi-qiang   

  1. Northern Jiangsu People’s Hospital, Yangzhou 225001, Jiangsu Province, China
  • Received:2015-12-02 Online:2016-02-19 Published:2016-02-19
  • Contact: Feng Xin-min, Chief physician, Professor, Master’s supervisor, Northern Jiangsu People’s Hospital, Yangzhou 225001, Jiangsu Province, China
  • About author:Zhang Liang, M.D., Associate chief physician, Lecturer, Northern Jiangsu People’s Hospital, Yangzhou 225001, Jiangsu Province, China
  • Supported by:

    the National Natural Science Foundation of China, No. 81401830; the Natural Science Foundation of Jiangsu Province of China, No. BK20140496

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Abstract:

BACKGROUND: Percutaneous vertebroplasty has been gradually used to treat Kümmell disease because of less trauma and quick pain relief, but there is still a high rate of bone cement leakage.
OBJECTIVE: To investigate the clinical efficacy of percutaneous vertebroplasty with high-viscosity bone cement plus hyperextension position reset for treatment of Kümmell’s disease.
METHODS: The clinical data of 17 patients with Kümmell’s disease were retrospectively analyzed, including 5 males and 12 females, aged 55-83 years, and all underwent percutaneous vertebroplasty with high-viscosity bone cement plus hyperextension position reset. The visual analog scale, Oswestry disability index score, vertebral body height and vertebral kyphosis angle were determined. The bone cement leakage, pulmonary embolism, adjacent vertebral fractures and other complications were recorded.
RESULTS AND CONCLUSION: At the 12th month of follow-up, the visual analog scale scores, Oswestry disability index scores and vertebral kyphosis angle of patients were significantly lower than those before treatment  (P < 0.05), the vertebral body height was significantly higher than that before treatment (P < 0.05). After treatment, there were three cases of bone cement leakage, which had no special discomfort and neurological symptoms, and one case of new fractures. These results demonstrate that hyperextension position reset combined with percutaneous vertebroplasty with high-viscosity bone cement in treatment of Kümmell’s disease can effectively relieve back pain, improve function of the lower back, partially restore vertebral height and reduce kyphosis angle.