Abstract:

BACKGROUND: Severe pain after artificial joint replacement is an important factor for successful rehabilitation. Painless after artificial joint replacement is a hot issue.
OBJECTIVE: To explore the effect of cyclooxygenase-2 inhibitor and ropivacaine infiltration analgesia around hip in primary total hip arthroplasty (THA).
METHODS: A total of 40 patients who underwent primary THA were randomized into two groups and received wound infiltration at the end of surgery. Trial group received 200 mg cyclooxygenase-2 inhibitor 2 hours before THA and 0.15% ropivacaine 100 mL following THA, followed by cyclooxygenase-2 inhibitor. Control group were injected with normal saline. All patients used patient-controlled analgesia to reduce pain for 24 hours after THA.
RESULTS AND CONCLUSION: The 24-hour patient-controlled analgesia requirement postsurgery was less compared with the control group with less adverse effects. Periarticular intraoperative injection with ropivacaine and cyclooxygenase-2 inhibitor can relieve pain in patients undergoing THA and is a safe analgesia method.