Chinese Journal of Tissue Engineering Research ›› 2010, Vol. 14 ›› Issue (47): 8889-8892.doi: 10.3969/j.issn.1673-8225.2010.47.037

Previous Articles     Next Articles

Nano-hydroxyapatite/polyamide 66 artificial vertebrae implantation for vertebral reconstruction

He Bin, Jiang Dian-ming, Ou Yun-sheng, Quan Zheng-xue, Tang Ke   

  1. Department of Orthopedics, The First Affiliated Hospital of Chongqing Medical University, Chongqing Spinal Surgery Center, Chongqing   400016, China
  • Online:2010-11-19 Published:2010-11-19
  • Contact: Jiang Dian-ming, Professor, Doctoral supervisor, Department of Orthopedics, The First Affiliated Hospital of Chongqing Medical University, Chongqing Spinal Surgery Center, Chongqing 400016, China jdm571026@ vip.163.com
  • About author:He Bin★, Studying for master’s degree, Attending physician, Department of Orthopedics, The First Affiliated Hospital of Chongqing Medical University, Chongqing Spinal Surgery Center, Chongqing 400016, China nact5@sohu.com
  • Supported by:

    the National High-tech R&D Program of China (863 Program), No. 2002AA326020*; National Science &Technology Pillar Program During the Eleventh Five-Year Plan Period, No. 2007BAE13B04*

Abstract:

BACKGROUND: Thoracolumbar vertebral eosinophilic granuloma is uncommonly encountered in clinical practice. Vertebral body replacement with different biological materials is used for the reconstruction of the osseous defect after corpectomy. But it has been few researched about the nano-hydroxyapatite/polyamide 66 artificial vertebral body in the clinical application of the disease until now.
OBJECTIVE: To observe the efficacy of nano-hydroxyapatite/polyamide 66 artificial vertebral body on the vertebral reconstruction of eosinophilic granuloma after corpectomy.
METHODS: Fifteen patients with thoracolumbar vertebral eosinophilic granuloma confirmed by pathological detection were admitted to Department of Orthopedics at the First Affiliated Hospital of Chongqing Medical University from January 2005 to December 2009, their therapeutic effects were retrospectively analyzed. All the cases underwent anterior lesions removal, implantation of nano-hydroxyapatite/polyamide 66 artificial vertebral body, and anterior screw-plate fixation system. The incision healing, wound complication and recovery of spinal cord function were determined.
RESULTS AND CONCLUSION: All 15 patients followed up for a mean of 2.1 years, all of them were cured without recurrence and complications. The spinal cord function recovered. After removal of vertebral eosinophilic granuloma, implantation of nano-hydroxyapatite/polyamide 66 artificial vertebral body, and anterior screw-plate fixation system can obtain good therapeutic effect of vertebral reconstruction.

CLC Number: