Chinese Journal of Tissue Engineering Research ›› 2012, Vol. 16 ›› Issue (52): 9802-9806.doi: 10.3969/j.issn.2095-4344.2012.52.022

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Design of the intraoperative imaging navigation system based on the near-infrared fluorescence properties of indocyanine green

Lü Tie-jun, Li Wen-ke, Li Kai-yang   

  1. College of Physical Science and Technology, Wuhan University, Wuhan 430072, Hubei Province, China
  • Received:2012-05-22 Revised:2012-08-05 Online:2012-12-23 Published:2012-12-23
  • Contact: Li Kai-yang, Doctor, Professor, Doctoral supervisor, College of Physical Science and Technology, Wuhan University, Wuhan 430072, Hubei Province, China lky@whu.edu.cn
  • About author:Lü Tie-jun★, Studying for master’s degree, College of Physical Science and Technology, Wuhan University, Wuhan 430072, Hubei Province, China lvtiejun@whu.edu.cn

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Abstract:

BACKGROUND: In recent years, indocyanine green has been used in some medical imaging because of its unique physical properties and near-infrared spectral characteristics.
OBJECTIVE: To design an intraoperative imaging navigation system based on the near-infrared fluorescence properties of indocyanine green.
METHODS: The optical part, hardware part and software part were designed according to the principle. The imaging efficacy of system was identified through early experiment.
RESULTS AND CONCLUSION: Conventional method of providing intraoperative anatomical information was used to transfer the preoperative image data of specific tissues to intraoperative situation. However, that was difficult in some cases. So, it was important to provide real-time information for the biological tissues by intraoperative imaging. The experimental results of human blood in imaging system show the intraoperative imaging navigation system based on the near-infrared fluorescence properties of indocyanine green has high fluorescence induction, apparent distinct and better imaging quality, which indicates the feasibility of the design proposal.

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