Chinese Journal of Tissue Engineering Research ›› 2010, Vol. 14 ›› Issue (51): 9675-9678.doi: 10.3969/j.issn.1673-8225.2010.51.041

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Biocompatibility of different induction materials for bone injury repair

Wang Qing-feng   

  1. Physical Education College, Henan Polytechnic University, Jiaozuo   454000, Henan Province, China
  • Online:2010-12-17 Published:2010-12-17
  • About author:Wang Qing-feng, Associate professor, Physical Education College, Henan Polytechnic University, Jiaozuo 454000, Henan Province, China

Abstract:

OBJECTIVE: To elaborate the necessity and importance of understanding the biocompatibility of biomaterials in tissue engineering rehabilitation process.
METHODS: A computer-based online search of PubMed database and CNKI database was performed by the first author, using the key words of “acute injury, bone, biological material” in English and in Chinese to search the title and abstract. Articles related to treatment approach of acute bone injury, materials science characteristics, biocompatibility and its application effect were selected, a total of 20 articles were included in analysis.
RESULTS: Early treatments for bone tissue engineering are autologous and allogeneic transplantations, both are defective, the former is easy to cause secondary injury in patients, the later is faced with greater bio-security risk, so artificial biomaterials for bone tissue repair has been attracting more and more attention in clinical practice. Currently artificial bone graft biomaterials include bone-derived materials, polymer materials, inorganic materials and composite materials, these materials have a repair, replacement and regeneration effect on the body tissue, in which a good biocompatibility of the biomaterials plays a vital role in the application success.
CONCLUSION: The ideal choice of biomaterials must attach importance to its good biocompatibility, which directly determines the rehabilitation of bone, a good biocompatibility is the basis and the necessary conditions for biomaterials choice in tissue engineering treatment process.

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