Chinese Journal of Tissue Engineering Research ›› 2010, Vol. 14 ›› Issue (9): 1677-1680.doi: 10.3969/j.issn.1673-8225.2010.09.037

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Occurrence factor and preventive strategy for deep venous thrombosis following artificial hip replacement

Ma Li1, Wang Xin2, Jiang Li-hua3   

  1. 1Surgery Room of Clinical Experimental Center, Shenyang Medical College, Shenyang  110034, Liaoning Province, China;
    2Department of Surgery, Shenyang Fourth People’s Hospital, Shenyang  110034, Liaoning Province, China
  • Online:2010-02-26 Published:2010-02-26
  • About author:Ma Li, Senior experimentalist, Surgery Room of Clinical Experimental Center, Shenyang Medical College, Shenyang 110034, Liaoning Province, China mali1958@sina.com

Abstract:

OBJECTIVE: A series of studies has been reported concerning deep venous thrombosis following artificial hip replacement. This paper is aimed to summarize the occurrence factor and preventive measures for deep venous thrombosis following artificial hip replacement.
METHODS: A computer-based online search of VIP database was undertaken by the first author to identify the articles about the deep venous thrombosis following artificial hip replacement published in between January 1994 and October 2009 with the key words of “artificial hip replacement and deep venous thrombosis”. Inclusive criteria: ①Occurrence factor of deep venous thrombosis following artificial hip replacement. ②Diagnostic criteria and diagnostic methods of deep venous thrombosis following artificial hip replacement. ③Preventive strategy for deep venous thrombosis following artificial hip replacement. Inclusive criteria: repetitive research or obsolete documents. Totally 25 literatures were included in this paper.
RESULTS: The agreement has been basically achieved for pathogenesis and risk factor of deep venous thrombosis following artificial hip replacement. The pathogenesis included blood hypercoagulable state, slow blood flow (or stasis), and vessel wall damage. Meanwhile, elderly, cerebrovascular disease, varicose vein or intravenous surgery, were the risk factors of deep venous thrombosis. Mechanical therapy or medication could be selected for preventing patients against deep venous thrombosis following artificial hip replacement with different features. It was an acceptable method for most patients using mechanical therapy, which could not induce drug adverse reaction, but the clinical efficacy remained uncertain for high-risk patient population, thus, medication should be combined. Low molecular heparin was considered first-choice drugs for preventing deep venous thrombosis following artificial hip replacement, which was characterized by common uses and reliable effects.
CONCLUSION: Studies on influencing factor and preventive treatment of deep venous thrombosis following artificial hip replacement has arisen more attention in medical circles. The understanding of pathogenesis, correlation factors and preventive measures plays an important role in decreasing incidence deep venous thrombosis.

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